oxygen-glucosedeprivation相关论文
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Oxygen-glucose deprivation induces the pathological changes of neurites in cultured hippocampal neur
Objective: Alzheimers disease(AD)is a neurodegenerative disease.The two obvious neuropatholopgical changes in AD are sen......
Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial c
Aim: Accumulating evidence implicates that the endothelial injury contributes to the ischemic neurovascular damage.This ......
Objective P2X7 receptor contributes to pathophysiological changes of ischemic diseases....
Inhibition of autophagy aggratated oxygen-glucose deprivation/reperfusion induced neuron injury in v
Objective Several lines of evidences indicated that autophagy was involved in ischemic brain injury.Ischemia/reperfusion......
Ischemic stroke is the leading cause of ischemia-related death globally.Brain injuries due to stroke and trauma are typi......
Hemichannels or gap junctions contributed to neuronal ischemic tolerance induced by astrocyte-condit
As a main subtype of gtia in the central nervous system, astrocytes have diverse and comprehensive functions, from nutri......
Objective TRPM7, as a divalent cation channel plays an important role in neurons damaged from cerebral ischemia due to p......
Hydroxysafflor yellow A protects neurons from excitotoxic death through inhibition of NMDA receptors
Excessive glutamate release causes over-activation of NMDARs,leading to excitatory neuronal damage in cerebral ischemia.......
Objective: Caveolin-1 (Cav-1) is the main structural protein of caveolae, the micro-invaginations of the plasma membrane......
Protective Effect of Salidroside on Mitochondrial Disturbances via Reducing Mitophagy and Preserving
Salidroside is the active ingredient extracted from Rhodiola rosea,and has been reported to show protective effects in c......
Objective: Autophagy serves as a stress response and it is a process involved in neurodegeneration diseases. Increas......
Brain-derived neurotrophic factor (BDNF) has robust effects on synaptogenesis, neuronal differentiation and synaptic tra......
目的 研究低氧诱导因子(HIF)-1α是否介导缺糖缺氧诱导的原代皮质神经元caspase非依赖性细胞死亡,Necrostain-1( Nec-1)能否抑制其......
目的探讨氧糖剥夺(oxygen-glucose deprivation，OGD)条件下脑星形胶质细胞缝隙连接与糖摄取功能之间关系。方法取出生1 d的SD大鼠大......
Oxygen-glucose deprivation regulates BACE1 expression through induction of autophagy in Neuro-2a/APP
Our previous findings have demonstrated that autophagy regulation can alleviate the decline of learning and memory by el......
Alcohol, a widely abused drug, has deleterious effects on the immature nervous system. This study investi-gates the effe......
目的观察重组人神经调节蛋白（recombinant neuregulin-1beta，rhNRG）-1β在氧和葡萄糖剥夺（oxygen-glucose deprivation，OGD）条件下通过细......
目的：观察糖氧剥夺对星形胶质细胞（Astrocyte，Ast）的影响及腺苷的保护作用。方法：体外培养SD大鼠大脑皮层Ast，培养至第四代时传代至96孔......
